So you're faced with two choices: you can either leave the mixed media artwork on vellum unsealed, and just carefully protect it by getting it framed safely behind glass or you can take your chances and use a spray varnish. the spray might not sink into the vellum well enough for it to properly adhere and dry, which means that the sealant would remain runny and possibly smear the watercolors.form small puddles on the vellum, thus causing it to warp, or.If you are using paper vellum, the danger with using a spray sealant is that the spray might either: If you are using vellum made from calfskin, you should be able to lightly spray it with a product like Krylon Crystal Clear, which will sink into the calfskin vellum and seal your mixed media artwork. (I'm assuming from the title of your question that you are using paper vellum.) modern vellum, which is a paper form of imitation vellum, created from plasticized cotton.

vellum made from calfskin, which is the 'original' kind of vellum used by artists for centuries for paintings and manuscripts, or.Now comes the question: which type of vellum are you using: This means that you will need to spray your artwork in order to seal it. In your case, brushing anything over the watercolors will only cause it to smear and ruin the piece. Since your mixed media artwork includes watercolors, you can't brush on a sealant - otherwise I would suggest lightly brushing the artwork with an acrylic medium, such as Golden Gloss Medium (this links to Blick Art Materials, and if you make a purchase I get a small commission that helps support this site). Safely sealing your mixed media artwork on vellum is a tricky conundrum.

Calfskin vellum